At Deluxe Med Spa and Wellness, we bridge the gap between mechanical skin repair and advanced cellular signaling. Microneedling with PRP or serum infusions uses precision micro-channels to deliver bioactive compounds deep within the skin, where they help accelerate collagen synthesis and structural remodeling. While standard microneedling relies solely on a wound-healing response, these enhanced protocols provide the specific chemical signals your cells need to firm, smooth, and rejuvenate. Because no two complexions are identical, we customize your treatment by selecting specific PRP or serum blends tailored to your skin’s unique needs.
This treatment combines mechanical stimulation with targeted chemistry to change how your skin behaves. While the microneedling process triggers a natural renewal cycle, the topical PRP or serum infusions act as a specific signal, directing your cells to repair and strengthen the tissue.
We select specific PRP or serum blends based on your unique skin concerns, focusing on either firming, texture, or hydration, so your cells receive the exact instructions they need for repair. This combination helps support the formation of stronger, higher-quality collagen than microneedling alone can achieve.
Microneedling with PRP or serum is safe for all skin types and tones, and suitable for a wide range of skin concerns. It works well for clients who want structural improvement with minimal downtime. Ideal candidates typically present with:
At Deluxe Med Spa and Wellness, we match each serum infusion to your skin’s specific biology. During your consultation, we identify whether your tissue requires peptides focused on firming, calming inflammation, or clearing pigment.
Fine lines and early to moderate skin laxity in the face, neck, or décolletage
Loss of skin density or a general softening of facial contours
Dull, dehydrated, or devitalized skin that lacks bounce and resilience
Every microneedling with PRP or serum infusion session at Deluxe Med Spa and Wellness is built around one principle: getting the right ingredients to the right depth, at the right concentration, for your specific skin.
Your clinician begins by thoroughly cleansing the treatment area and applying a topical anesthetic to ensure you’re comfortable throughout the procedure. The microneedling device is then guided across the skin, creating thousands of precisely calibrated micro-injuries at a depth determined by your skin’s individual profile and the concerns we’re targeting. Your PRP or serum infusion is then applied while those channels are open, allowing it to reach the deeper layers of the tissue where it can signal change at a cellular level. Most full facial sessions are completed in 45-60 minutes.
PRP and serum infusions work by binding to receptors in the skin and communicating with fibroblasts, the cells responsible for producing collagen, elastin, and other structural proteins. The problem is that intact skin is a highly effective barrier. Without a delivery system, most infusions cannot get through the surface layer in sufficient amounts to stimulate collagen production. Microneedling changes that by bypassing the skin’s surface defense and placing serums exactly where their signaling properties can take effect.
Serum formulations vary significantly in their target function; some are designed for structural lifting and firmness, others focus on scar tissue, barrier reinforcement, or brightening. Your provider will select the appropriate formulation based on your skin assessment results and your primary goals. The device depth, pass count, and product selection are all adjusted to your skin.
Microneedling with PRP or serum infusions delivers clinical-level results with a recovery that fits into real life.
Days 1-5: The microchannels close as your skin shifts into active repair mode. Serums are actively binding to dermal receptors and initiating fibroblast signaling. Skin often feels more hydrated and looks subtly brighter during this early phase.
Weeks 2-4: New collagen fibers begin organizing in the dermis. Texture smooths noticeably, pore appearance refines, and the overall skin surface feels more even.
Weeks 4-8: This is when the cumulative structural work becomes visible. Skin density increases, facial contours feel more defined, and concerns like acne scarring and uneven tone show measurable improvements as the remodeling process matures.
The skin will appear flushed and may feel warm or slightly sensitive to the touch, which is a predictable response to microneedling that signals the repair process has begun. Any visible redness or minor swelling generally clears within 24-48 hours. You can return to your regular activities the same day. For the remainder of the treatment day, skip the gym, steam rooms, and direct sun exposure. Going forward, a broad-spectrum SPF 30 or higher is non-negotiable, as newly stimulated skin is more vulnerable to UV-induced pigmentation, and protecting it is part of protecting your results.
A series of 3-4 treatments spaced approximately 4 weeks apart gives each round of collagen production time to build on the last. Clients who are in a maintenance phase to preserve results rather than build them usually return every 3-6 months.
Microneedling with PRP pricing is per session. Your provider will confirm the best protocol for your goals at your complimentary assessment.
Package pricing is available — ask your provider about current promotions at your consultation.
Locations
Microneedling with PRP — available at all five Southern California locations.
1241 Grand Ave #H, #C
Diamond Bar, CA 91765
(909) 686-8888
2646 Dupont Dr., Suite 250
Irvine, CA 92612
(949) 350-8889
2630 West Olympic Blvd
Los Angeles, CA 90006
(213) 900-9777
17188 Colima Rd #B
Hacienda Heights, CA 91745
(626) 686-8666
2415 E Imperial Hwy, Suite A
Brea, CA 92821
(714) 660-5888
If you’re looking to improve skin texture, firmness, or overall skin quality with a treatment that works at a cellular level, microneedling with PRP or serum infusions is worth a conversation. At Deluxe Med Spa and Wellness, we’ll start with a thorough skin assessment to understand what your skin actually needs before recommending anything. From there, we build a protocol around your goals, including the right serum formulation, treatment depth, and session cadence, specifically for your skin. Visit us at any of our locations across Los Angeles, Irvine, Diamond Bar, Hacienda Heights, or Brea, to get started.
1241 Grand Ave #H, #C, Diamond Bar, CA 91765
2646 Dupont Dr., #250, Irvine, CA 92612
2630 West Olympic Blvd, Los Angeles, CA 90006
17188 Colima Rd #B, Hacienda Heights, CA 91745
2415 E Imperial Hwy, Suite A, Brea, CA 92821